Open Funding Opportunities
The Advanced Research Projects Agency for Health (ARPA-H) funds transformative health breakthroughs using diverse funding mechanisms. These mechanisms allow us to address the critical health challenges that traditional research and private industry cannot.
Below are the areas in which ARPA-H is currently soliciting research applications. Solicitations are time-limited. Check back regularly for new programs. For application details, visit our Submission Resources and FAQs page.
Programs
ARPA-H's program managers (PMs) are at the center of our work. PMs start with a big idea that, if successful, could transform health care. This idea forms the basis of each program.
PMs seek diverse research performers, generally through Program-specific Innovative Solutions Openings (ISOs). ISOs are usually accompanied by a Proposers’ Day, during which potential performers can meet PMs to learn program details and network. Interested proposers should read solicitations carefully to understand what ARPA-H is seeking. We welcome ideas and proposals from all sources, and we encourage researchers to ask the appropriate ARPA-H representatives any questions prior to submission. Solicitations are open for a limited time.
ARPA-H is committed to fair consideration of all proposals. We recognize the investment of time and resources in applications.
Open Program Solicitations:
Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST)
Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE)
Health Care Rewards to Achieve Improved Outcomes (HEROES)
Platform Optimizing SynBio for Early Intervention and Detection in Oncology (POSEIDON)
Mission Office ISOs
Mission Office Innovative Solutions Openings (ISOs) provide a mechanism for potential performers to seek funds for research projects that do not fit within the scope of an existing program.
Each of the ARPA-H Mission Offices – Health Science Futures, Proactive Health, Resilient Systems, and Scalable Solutions – accepts applications on a rolling basis and makes awards based on a wide variety of factors. Read each ISO description carefully to ensure your submission is appropriate to the specific Mission Office.
Important Note: Before applying to a Mission Office ISO, review ARPA-H's Program ISOs first to see if one of the agency’s programs would be a good fit for your idea. A submission to a Mission Office ISO may be rejected if its within the scope of an existing program.
Open Mission Office ISOs:
Small Business Awards
Our Small Business Program provides Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) awards fund small business that can contribute to the agency’s mission. ARPA-H uses a simplified application and review process to ensure that businesses receive funding up to 75% faster than usual. We also offer consulting services to help accelerate the commercialization of products. Topics of interest for the ARPA-H Small Business Program are updated regularly in response to the changing needs of the agency. Potential applicants should carefully view topics or opportunities to determine whether their ideas reflect what ARPA-H is looking for in submissions.
Open Small Business Solicitations:
There are currently no open Small Business solicitations.
Research Sprints
ARPA-H supports research sprints that aim to rapidly accelerate research innovation in a specific area. For instance, during our inaugural Sprint for Women’s Health, the agency sought to address women’s health challenges across a range of topics. Each sprint runs for only a short period of time and aims to make rapid change in a targeted area of need.
Open Sprints:
There are currently no open Sprints.