AI has shown enormous promise to speed up biomedical research and development. Yet, its potential is limited by relying on graphics processing units (GPUs) that struggle with the growing complexity of large biomedical datasets. HYPERDRIVE aims to develop a new kind of AI acceleration hardware that leverages analog and digital computation to create faster, more energy-efficient hardware tailored for demanding biomedical algorithms. If successful, this novel analog AI processor could lead to faster discovery of life-changing medications for patients and to applications across advanced health technologies, from personalized medicine to AI-guided clinical diagnosis.