MAGNifying Glymphatics in Women’s Brains
What if we could identify neurophysiological sex disparity rationale in cognitive decline?
We seek to investigate the unique physiology of the meningeal lymphatic and glymphatic system. By leveraging the performance capabilities only accessible with the high-performance head-only 3.0-Tesla MRI gradient, we aim to develop a suite of tailored MRI acquisitions targeted to in-vivo functional and structural mapping of the brains meningeal lymphatic vasculature and glymphatic system and without contrast agent. With an emphasis on validation with healthy brains, we aim to shed light on the unique physiology of the systems behind the brain’s clearance mechanism as a function of both sex differentiation and age.
Topic 4: Women's Brain Health