Bioengineered Ex Utero Drug Testing Model
What if we definitively knew which medications were safe during pregnancy without needing to test these drugs?
More than 90% of FDA-approved drugs are not recommended for use during pregnancy, mostly because there are insufficient data to make conclusions about safety for the fetus. Our objective is to develop a model of human pregnancy that can be used to study how drugs interact with the placenta, the unique organ that protects and nourishes the fetus, and determine if certain drugs are safe. We intend to design a platform that will allow us to test dozens of drugs at a time. Our long-term vision is to use the platform to test all FDA-approved drugs, model pregnancy disorders, identify appropriate drug dosing, or even mimic clinical trials in the lab.
Topic 3: ARTEMIS: Modeling Sex Differences