In the United States alone, over 19,000 women are expected to be diagnosed with ovarian cancer in 2024. An effective treatment could save over 8,000 American lives each year, yet like many solid tumors, ovarian cancer does not respond effectively to current immunotherapies. A revolutionary approach in the fight against ovarian cancer has emerged thanks to the convergence of several technological and medical innovations. This new effort, called Targeted Hybrid Oncotherapeutic Regulation (THOR), will create a compact device designed to trigger the immune system against tumors. The device will be implanted in proximity of the tumor and will house specialized cells responsible for producing and delivering therapeutic molecules. These molecules will activate the immune system both locally around the tumor site and throughout the body. Additionally, the device will incorporate advanced sensors to detect and monitor biomarkers of cancer. The integration of these two components in a single device will enable precise delivery of therapeutic doses tailored to each patient’s needs.