What if discreet and low-cost wearable devices could help Americans continuously track deep biological information? 

The Problem 

• Devices that continuously monitor the body’s signals can offer key insights into health and wellness—but there is far more potential to explore. Currently, wearable or ingestible sensors provide only biophysical data, like heartrate, or metabolic data, like blood glucose. This narrow scope leaves out rich data streams that can prevent life-threatening health crises, better manage chronic conditions, safely recover from illness outside of a hospital, and improve overall wellness. 
• Today’s biosensors are bulky, expensive, and hard to update. Often, platforms are built with "one-off" design, focusing on only one component of health monitoring. This narrow approach means the biosensor industry continues to reinvent technology, slowing innovation and keeping costs high for people seeking useful information about their own bodies. 

The Solution 

• The Delphi program will spur a new development ecosystem that provides quick access to cutting-edge bioelectronics and sensing strategies. This approach will spur innovation with tiny, smart, next-generation “chiplets” that optimize delivery of real-time insights of important internal signals like hormones, immune markers, and therapeutic drug levels. 
• The “chiplet” platform will be designed to mix and match across a range of wearable and ingestible biosensors with a variety of sensing functions. This miniscule building block approach will pave the way for more accurate, affordable, and reliable devices. 
• This sophisticated technology will enable clinicians to track a broad range of biomarkers, and thereby detect the earliest signs of disease and remotely fine-tune treatments.  
• Perhaps even more importantly, it will enable all Americans to take ownership of their own health. Like the Greek legend of the oracle at Delphi, this program encourages Americans to “know thyself.” 

Only ARPA-H can... 

• Catalyze a daring overhaul of biosensor design, manufacturing, and packaging to enable continuous, real‑time monitoring of deep biological signals for everyone. 
• Leverage cutting‑edge chiplet microelectronics, ultra‑low‑power management, secure communications, and advanced bio‑interfaces to create modular sensors that can be rapidly reconfigured and reused across many health applications. 
• Empower top experts across diverse disciplines—microelectronics, materials science, bioanalytical chemistry, and cybersecurity— to build open, reusable architectures and standards that industry alone cannot develop. 
• Lower the barriers for bold prototypes that can be scaled and adopted by healthcare and consumer markets.