ARPA-H announces Mission Office-specific funding opportunity


ARPA-H announces Mission Office-specific funding opportunity 

New Innovative Solutions Opening (ISO) funding opportunities intend to pursue innovative high-impact biomedical and health research proposals 

The Advanced Research Projects Agency for Health (ARPA-H), an agency within the U.S. Department of Health and Human Services (HHS), today announced new funding opportunities through the launch of four Mission Office-specific Innovative Solutions Openings (ISO). Each Mission Office ISO seeks to fund groundbreaking new ways of tackling health-related challenges through innovative biomedical and health research.    

“As we launch into the second year of ARPA-H, the Mission Office Open ISOs are the next evolution for the agency in soliciting new, groundbreaking ideas to accelerate better health for everyone,” said ARPA-H Director Renee Wegrzyn, Ph.D. “Last year, we saw hundreds of exciting applications through our Agency-wide Open Broad Agency Announcement (Open BAA) that helped us build a truly unique portfolio that only ARPA-H can pursue. As we continue to grow our team and allow for more specialization across our Mission Offices, we know the research community will be excited to share their ideas on the next generation of breakthroughs in health that align more specifically to our Mission Office focus areas and strategic plan.” 

The Mission Office Open ISOs replace the existing Open BAA funding opportunity. Organizations that intended to submit to the Open BAA should now submit their proposal to one of the four Mission Office ISOs. The ISO focus areas are: 

  • Health Science Futures – Accelerating advances across research areas and removing limitations that stymie progress toward solutions for a broad range of diseases and conditions. 
  • Proactive Health – Creating capabilities to detect and characterize disease risk and promote treatments and behaviors to anticipate threats, whether viral, bacterial, chemical, physical, or psychological. 
  • Resilient Systems – Addressing systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care.
  • Scalable Solutions – Addressing challenges including geography, distribution, manufacturing, data and information, and economies of scale to develop impactful, timely, and equitable solutions. 

Each Mission Office ISO calls for proposals that outline revolutionary—not evolutionary— research and technological advancements. Proposals should investigate unconventional approaches and challenge accepted assumptions to enable leaps forward in science, technology, systems, or related capabilities. Awards made from each Mission Office ISO will generally be in the form of other transactions. Exact award amounts and continued support depend upon projects meeting aggressive research milestones, which is typical of the ARPA-H process.  

For more information and to submit a proposal visit the Mission Office ISO page